Apathy has been reported after pallidonigral lesions 55 and in a patient population with neurobehcet disease, affecting the brainstem and cranial nerves. An upper brainstem lesion has been reported to result in focal motor seizures repeatedly induced by alerting stimuli hirsch et al. The presentation of a patient with brainstem symptoms and signs invokes a number of common and less common differential diagnoses, and accurate diagnosis can be challenging. Explain the symptoms with regards to structures affected. Brain stem lesions brainstem animal anatomy free 30. This case serves to emphasise the importance of performing a thorough clinical exam while maintaining a high index of suspicion for brainstem lesions. Gates the geelong hospital, barwon health, geelong, victoria, australia the rule of 4 is a simple method developed to help students of neurology to remember the anatomy of the. The topography of the brainstem is complex, and even experienced neurologists find it challenging to localize brainstem lesions and diagnose brainstem disorders. We have recently reported that brainstem lesions may be responsible for the presence of seizures in patients with multiple sclerosis papathanasiou et al. In addition to primary brainstem lesions, such as vascular brainstem. So far the lesion could be anywhere in the medial aspect of the brainstem, although if the face is also affected it has to be above the mid pons, the level where the 7th nerve nucleus is.
Any information contained in this pdf file is automatically generated from. Differential diagnosis of t2 hyperintense brainstem lesions. Brainstem brainstem the lower extension of the brain where it connects to the spinal cord. Clinical approach to brainstem lesions sciencedirect. Pdf work out where the problem is in the brainstem using the rule. Brainstem disorders 2011th edition pdf download medical. Presentations of brainstem lesions can range from subtle. In this report, they describe a case of hemifacial spasms caused by a dysplastic neuronal lesion of the floor of the fourth ventricle. Guzmandevilloria, md, pilar fernandezgarcia, md, and concepcion ferreiroarguelles, md brainstem lesions can be classi. Diagnostic imaging, interventional treatment of brainstem lesions. Acute disseminated encephalomyelitis presenting as a solitary brain stem mass. While the contrast medium free tof method provides better spatial resolution, it occa sionally is rendered less diagnostic by turbulence caused by artifacts and is.
Case a 58 yo was referred to you because of recent onset of left hemiparesis, leftsided loss of propioception and rightsided tongue deviation. The spectrum of immunemediated and inflammatory lesions. Brainstem lesions tend to be centred on the cerebral peduncles and the pons, and may be circular, linear, crescentshaped or irregular in. Magnetic resonance imaging is the most suitable imaging modality for evaluating these lesions. The motor cranial nerve the parallels of latitude indicates whether the lesion is in the medulla 12th, pons 6th or midbrain 3rd. The topography of the brainstem is complex and even experienced neurologists find it challenging to localize brainstem lesions and diagnose brainstem disorders. Differential diagnosis of t2 hyperintense brainstem.
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